

This press release was originally published by BioAlliance Pharma; for a discussion of risks and uncertainties which could cause actual results, financial condition, performance or achievements of BioAlliance Pharma SA to differ from those contained in the forward-looking statements, please refer to the Risk Factors ("Facteurs de Risque") section of the 2008 Reference Document filed with the AMF on April 7, 2009, which is available on the AMF website or on BioAlliance Pharma SA's website
BioAlliance Pharma SA (Paris:BIO), a company dedicated to the treatment and supportive care of cancer and AIDS patients, today announced positive preliminary results from the first Phase I trial of fentanyl Lauriad®.
This first randomized, single-centre trial in healthy volunteers has evaluated the pharmacokinetics of a single application of 2 different innovative muco-adhesive formulations of fentanyl Lauriad®. The fentanyl was detected in the plasma soon after the application of each formulation and plasma concentrations remained stable over the next 24 hours, with low intersubject variability, especially for one of the two formulations that will be used for subsequent clinical development. Both muco-adhesive buccal formulations displayed a good local safety profile. These preliminary results suggest that a single daily application of fentanyl Lauriad® may provide effective relief of severe chronic pain in cancer patients. The company is planning to perform a second pharmacokinetic repeated-dose study by the end of the year.
"The success of this first Phase I clinical trial with fentanyl Lauriad® relies on our original know-how in mucosal drug delivery", explained Dominique Costantini, BioAlliance Pharma's President and CEO. "The Lauriad® technology has been extended to fentanyl and enables molecules which can cross the mucosa to remain in the body for long periods. This is a very important step on the path to clinical development for fentanyl Lauriad®".
About this first Phase I trial of fentanyl Lauriad®
This clinical trial was performed in healthy volunteers who were successively administered two innovative formulations one week apart according to a randomized design. The objective was to obtain stable fentanyl plasma concentrations over several hours. Fentanyl has already been shown to be systemically absorbed through the mucosal route leading to the development of fentanyl-based treatments for severe, acute pain. With the patented Lauriad® formulation, fentanyl is rapidly and continuously released in the oral mucosa and systemically absorbed. This concept of a sustained release addresses the treatment of cancer chronic pain.
About BioAlliance Pharma
As a preferred partner for hospital-based specialists, BioAlliance Pharma is a company which develops and markets innovative products in France, especially in the fields of opportunistic infections and chemotherapy complications. In areas where medical needs are insufficiently met, our targeted approaches help overcome drug resistance and improve patient health & quality of life. BioAlliance Pharma's ambition is to become a leading player in these fields by coupling innovation to patient needs.
Disclaimer
This communication expressly or implicitly contains certain forward-looking statements concerning BioAlliance Pharma SA and its business. Such statements involve certain known and unknown risks, uncertainties and other factors, which could cause the actual results, financial condition, performance or achievements of BioAlliance Pharma SA to be materially different from any future results, performance or achievements expressed or implied by such forward-looking statements. BioAlliance Pharma SA is providing this communication as of this date and does not undertake to update any forward-looking statements contained herein as a result of new information, future events or otherwise.
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Location: N. Thames
Salary: £30K plus bonus
Notes: <p>Territory Sales Manager<br />Continence Care<br />North Thames<br />Permanent<br />£30K plus bonus<br />1008-20<br />STAR's recruiting for a Territory Sales Manager opportunity within a leading European company. You'll develop effective relationships with key primary care and acute trust contacts to maintain existing business and create new clients within your territory. <br />We'd like to hear from candidates with a strong background in medical sales and dealt with both PCTs and clinical staff. You must have the confidence to discuss your products with your clients and an extensive knowledge of operating in the NHS environment.<br />If you would like to be responsible for your own territory and are driven to succeed, we would like to hear from you. If you would like to know more please call Nick on 01225 336 335 or email nick.loades@starmedical.co.uk</p>
Location: South West
Salary: £30K plus bonus
Notes: <p>Territory Sales Manager<br />Continence Care<br />South West<br />Permanent<br />£30K plus bonus<br />1008-19<br />STAR's recruiting for a Territory Sales Manager opportunity within a global company who have a heritage of more than 190 years. You'll develop effective relationships with key primary care and acute trust contacts to maintain existing business and create new clients within your territory. <br />We'd like to hear from candidates with a strong background in medical sales and dealt with both PCTs and clinical staff. You must have the confidence to discuss your products with your clients and an extensive knowledge of operating in the NHS environment.<br />If you would like to be responsible for your own territory and are driven to succeed, we would like to hear from you. If you would like to know more please call Richard on 01225 336 335 or email Richard.morris@starmedical.co.uk</p>
Location: South West & South Central London
Salary: £33-36K
Notes: <p>Account Executive<br />Capital Equipment<br />South West & South Central London<br />Permanent<br />Salary £33-36K Plus benefits<br />1008-27<br />STAR's recruiting for an Account Executive to maximise profitable rental opportunities with contracted accounts, drive new contract business and penetrate sales opportunities in acute units in South West & South Central London.<br />It's an important sales role in the assisted woundcare close therapy side of the business; you'll need to be a results orientated, self driven individual with a proven track record in sales. The ideal candidate will be an excellent communicator, face to face and over the telephone, with a natural ability to get on with others.<br />You must have capital sales experience, preferably within the pressure care market. A Tissue Viability qualification or wound care background is very desirable.<br />You'll be driven, focused and financially aware to meet your targets. You must be interested and motivated by the evolutionary process and able to think outside the box, whilst adhering to protocols and parameters. You need to be personable, with a good attitude to work, with excellent time management skills.<br />If you'd like to hear more about this exciting opportunity, call Stewart today on 01628 581240 or email your CV to us stewart.musselle@starmedical.co.uk</p>
Location: Basingstoke
Salary: Competitive
Notes: <p>Senior Product Manager<br /> <br />Neurology<br /> <br />Basingstoke<br /> <br />Permanent<br /> <br />Competitive Salary<br /> <br />1007-77<br /> <br />STAR's recruiting for a Product Manager opportunity based in Baisingstoke. This is an exciting opportunity to be working in a highly specialised therapeutic market place.<br />You'll be responsible for the day to day programme support for products in UK and Ireland consistent with agreed strategies and expenditure.<br />In collaboration with Marketing, you will be responsible for all aspects of creating and implementing a market access plan for your assigned products. You'll be responsible for optimising results by developing and implementing effective programmes, consistent with EU and global strategies. Developing pre-launch and launch plans with commercial and medical management teams will also be key for new products in this role. You'll provide a regular input at brand team meetings and to patient outcome surveys for the products. As part of this role, you'll manage the marketing budgets to ensure that it remains consistent with the agreed budget plan and demonstrate an effective spend/sales ratio. <br />The ideal candidate will be educated to degree level or equivalent in life sciences and have experience in product launches and market access strategy. You'll be able to prioritize and deliver key projects within agreed timescales. A self starter and team player who has worked at a management level, you must have experience of secondary care products.<br />You'll be an excellent communicator, have good time management skills and be able to build strong relationships both internally and externally. We'd like to speak to people who have a strong scientific knowledge base and are organised and able to be flexible in a changing environment.<br />If you're interested in this opportunity please email a copy of your CV to samantha.wise@starmedical.co.uk or call Samantha on 01628 581 240</p>
Location: Watford
Salary: Up to £60K plus bonus
Notes: <p>Product Manager<br />Watford<br />Permanent<br />Up to £60K plus bonus<br />Competitive Salary<br />1008-22<br />STAR's recruiting for a Product Manager implementing effective strategy to achieve increased sales of prescription only medicines to pharmacies.<br />You'll be responsible for commissioning market research into ideal promotional platforms and key messages for your products and create launch and development plans using this information. A large part of your role will be to identify and maximise new marketing and sales opportunities as well as a rolling strategic plan for your assigned products. Monitoring of your sales team's activity and performance against assigned targets and budgets.<br />The ideal candidate will be educated to degree level or equivalent in a marketing area, with comprehensive experience in pharmaceutical sales and marketing. You'll need excellent verbal and written communication skills to succeed in this role, combined with the ability to both self-motivate and collaborate with relevant teams to achieve given targets.<br />If you would like to know more about this role, please call Samantha on 01628 581 240 or email a copy of your C.V. to samantha.wise@starmedical.co.uk</p>
Location: Berkshire
Salary: Up to £45K
Notes: <p>Associate/Brand Manager<br />Immunology/Gastroenterology<br />Berkshire<br />Up to 45K plus benefits<br />Permanent<br />1008-26<br />STAR's recruiting for a new Brand Manager opportunity. In this role you'll be developing and implementing sales strategies to maximise return.<br />You'll be creating, implementing and managing impactful marketing programmes at a sales force level. Responsible for ensuring that the budget remains within agreed limits, you will liaise closely with the sales management and sales teams to ensure full engagement with pre determined campaigns and brand plan. With this in mind you will need to develop effective ways to implement company strategy and assess ROI through KPIs.<br />We would like to hear from candidates who are educated to degree level or equivalent and have experience in project development and implementing strategic marketing plans, with good knowledge of the marketplace. Demonstrable sales record in the Pharmaceutical or Healthcare sector. You'll have the ability to grasp complex information and react accordingly within your key customer environment. You must have excellent interpersonal skills and previous experience of digital media communication would be an advantage. Computer literacy in and fluency in English are important assets for your role. <br />If you are a self starter who would like to work in an growing company we would like to hear from you.<br />If you'd like to know more please call David Alexander on 01225 336 335 or mail your CV to david.alexander@starmedical.co.uk</p>
Location: East Midlands
Salary: Competitive
Notes: <p> </p> <p>Hospital Sales Specialist</p> <p>East Midlands (Nottingham, Leicester, Derby, Lincoln)</p> <p>Circa 48K</p> <p>Oncology</p> <p>Permanent</p> <p>1008-25</p> <p>We have an exceptional Hospital Specialist vacancy available with a company devoted to the discovery and development of innovative diagnostic and therapeutic products, with a promising pipeline to match!</p> <p>On a daily basis you'll secure meetings and develop relationships with key NHS and private customers in your area including doctors, registrars, nurses, pharmacists, managers and other oncology unit staff.</p> <p>You'll position and sell the product by providing detailed, useful, tailored information about its benefits, based on your product knowledge, which you'll have to keep up to date.</p> <p>To be successful in this role, you should be able to demonstrate proven success in hospital sales. Ideally, you'll have oncology, and strong PCT experience. We would like to hear from you if you're currently a Hospital Specialist, with experience in a niche area. Key Account Management experience is would be advantageous, as well as a good understanding of clinical papers and ability to use them to sell effectively. A life science degree or equivalent or qualification in nursing, pharmacy or a related field is an essential to this position.</p> <p>If you'd like to hear more about this exciting opportunity call Nick today on 01225 336335 or email your CV to us at <a href="mailto:nick.loades@starmedical.co.uk">nick.loades@starmedical.co.uk</a></p> <p> </p> <p> </p> <p> </p>
Location: North of England
Salary: Up to 33K
Notes: <p>Area Sales Manager<br />North of England (North West, North East and Scotland)<br />Permanent<br />Up to £33K<br />1008-24<br />STAR's recruiting for an Area Sales Manager, delivering profitable sales against agreed targets. In this role you will be responsible for effectively promoting and selling products according to internal and external customer needs. Adhering to operating procedures and maintaining awareness of activity in your territory and ensuring that customers are up to date on technical developments. You'll be seeking out new business opportunities as well as maintaining current client relationships. Delivering monthly product, activity and sales reviews to Management will be an important part of your role as maintaining a positive image and consistency of business is vital.<br />The ideal candidate will be educated to degree level of equivalent with demonstrable selling skills into hospitals and the NHS. Knowledge of pharmacy and aseptic units would be a huge benefit to you in this role, as well as an in-depth knowledge of the NHS, capital equipment and disposables. You'll need experience of creating and conducting presentations as this will be a large part of your role.<br />If you are a highly motivated self-starter, please call Stewart on 01628 581 240 or email a copy of your C.V. to stewart.musselle@starmedical.co.uk</p>
Location: Coventry, Northampton, Milton Keynes, Luton, Oxford, Reading, High Wycombe, Hemel Hempstead, Slough
Salary: Competitive
Notes: <p>Territory Manager<br />Woundcare & Skin<br />Coventry, Northampton, Milton Keynes, Luton, Oxford, Reading, High Wycombe, Hemel Hempstead, Slough (Postcode CV, NN, MK, LU, OX, RG, HP, SL, WD, AL, EN, SG)<br />Competitive salary<br />Permanent<br />1008-31<br />STAR has an exciting new Territory Manager opportunity, in which you'll be responsible for driving sales and market share by building relationships with NHS personnel and customers, ensuring high performance is delivered at all times. <br />You'll be working in our client's Woundcare & Skin division, selling a range of intimate healthcare products.<br />We welcome applications from individuals with experience of working in a sales environment, ideally medical devices or healthcare, and of client negotiation at senior, clinical level. <br />A Bachelor degree or equivalent qualification is very desirable, and experience of working with supplies/procurement would be extremely advantageous. <br />If you'd like to hear more about this exciting opportunity, call Nick today on 01225 336335 or email your CV to Nick at Nick.Loades@starmedical.co.uk</p>